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Corewell Health System, Hematology

Schistocyte Review Test Now Available to Order

Effective Wednesday, April 29, 2026, Schistocyte Review (LAB1231565) will be available to order across all Corewell Health Laboratories Hematology Departments.

This new orderable supports alignment across Corewell Health regions by standardizing schistocyte assessment practices, ensuring high‑quality testing, and delivering a consistent patient care experience system‑wide

Schistocytes are red blood cell (RBC) fragments that lack central pallor. They are seen in severe burns, disseminated intravascular coagulation (DIC), thrombotic thrombocytopenic purpura (TTP), microangiopathic hemolytic anemias, and other causes of mechanical hemolysis.

The orderable will always be performed by techs under the microscope and involve examination of the red blood cell (RBC) morphology  to determine the average number of schistocytes observed in at least 8-10 fields.  It will be resulted as none seen, few, moderate, or many.

References:

  • Tefferi A, Elliott M, Schistocytes on the Peripheral Blood Smear, Mayo Clinic Proceedings, 79809
  • Scordino, Teresa, Schistocytes, American Society of Hematology Image Bank, January 2016

 

Advanced Technology Laboratory

New Test Available: Myxoid Liposarcoma Panel by FISH

We are pleased to announce the launch of the Myxoid Liposarcoma Panel by Fluorescence in situ Hybridization (FISH), now available for clinical ordering on Formalin-fixed, paraffin-embedded (FFPE) tissue.

The Myxoid Liposarcoma Panel by FISH includes:

  • CHOP (DDIT3) (12q13) Rearrangement
  • FUS (16p11) Rearrangement

These probes may also be ordered individually.


Test Ordering Information


Questions? We’re Here to Help

For additional clinical details or follow-up questions regarding this test, please use the contact us link above.

Southwest Michigan, West Michigan

Testosterone Testing and Ordering Recommendations

Effective March 4, 2026, Corewell Health Laboratories in West Michigan will discontinue performing testosterone testing (LAB173 and LAB2111222) and Corewell Health Southwest Michigan will discontinue Testosterone Free and Total testing (LAB173)

The following replacements will be available as a send out to Quest Diagnostics:

Testosterone, Total, MS – Epic Code: LAB1232313

Testosterone, Free, Bioavailable and Total, MS – Epic Code: LAB1232237 Continue Reading

Corewell Health System, Emergency, Inpatient

New Test: Antiphospholipid Antibody Panel (Inpatient and Emergency Department)

Effective March 4, 2026, an Antiphospholipid Antibody Panel will be available for adult patients in the emergency, observation, and inpatient settings across the Corewell Health System.

This update is intended to streamline the ordering of appropriate hypercoagulation and thrombophilia testing in alignment with current evidence‑based best practices.

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Referral/Sendouts

Send Out Referral Testing Update: Phase Two Transition to Quest Diagnostics

Go-Live Date: December 17, 2025

Following Phase One in November, where tests previously referred to ARUP and some Mayo Clinic Lab tests were transitioned to Quest Diagnostics, we are now moving into Phase Two of this important change. Corewell Health Laboratory is continuing its transition to Quest Diagnostics as our primary reference testing partner.

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Referral/Sendouts, Southeast Michigan, Southwest Michigan, West Michigan

Primary Reference Lab Change to Quest Diagnostics

Effective November 19, 2025

Corewell Health Laboratory is transitioning to Quest Diagnostics as our primary reference testing laboratory. This change means that nearly all referral and send-out tests will now be performed by Quest Diagnostics. A limited number of tests will continue to be sent to other laboratories to ensure we meet the needs of our patients and clinicians.

What You Need to Know:

  • Test Crosswalks: Tests currently performed at ARUP and Mayo Clinic Labs will be matched to comparable tests at Quest Diagnostics.
  • Discontinued Tests: Tests with low utilization or those no longer deemed clinically necessary will be discontinued.
  • New LAB Numbers: All tests will receive new LAB numbers, which must be updated in your EMR compendium if interfaced.
  • Collection Devices: Some tests may require different collection devices.
  • Transition Timeline:
    • November 19, 2025: Focus on tests currently referred to ARUP.
    • December 17, 2025: Focus on tests currently referred to Mayo Clinic Labs.
  • Crosswalk Resources: Crosswalks between current and future test offerings will be provided to help you prepare.
  • Test Directory Access: Please refer to your regional Lab Test Directory for details on specific test changes. ARUP and Mayo Clinic Lab test pages will include links to the corresponding Quest Diagnostic tests.

We understand the significance of these changes and are committed to supporting your practice throughout this transition. Updates and modifications will be communicated promptly.

Contact Information:

  • Corewell Health East Sendouts: 248.551.9045
  • Corewell Health West Referrals: 616.267.2753
  • Or use the Contact Us link above.