Effective Wednesday, April 29, 2026, Schistocyte Review (LAB1231565) will be available to order across all Corewell Health Laboratories Hematology Departments.
This new orderable supports alignment across Corewell Health regions by standardizing schistocyte assessment practices, ensuring high‑quality testing, and delivering a consistent patient care experience system‑wide
Schistocytes are red blood cell (RBC) fragments that lack central pallor. They are seen in severe burns, disseminated intravascular coagulation (DIC), thrombotic thrombocytopenic purpura (TTP), microangiopathic hemolytic anemias, and other causes of mechanical hemolysis.
The orderable will always be performed by techs under the microscope and involve examination of the red blood cell (RBC) morphology to determine the average number of schistocytes observed in at least 8-10 fields. It will be resulted as none seen, few, moderate, or many.
References:
- Tefferi A, Elliott M, Schistocytes on the Peripheral Blood Smear, Mayo Clinic Proceedings, 79809
- Scordino, Teresa, Schistocytes, American Society of Hematology Image Bank, January 2016
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