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Test Update

General Information, Hemostasis/Coagulation

Test Update: Prothrombin Time (Protime/PT)

Effective December 6, 2021, Spectrum Health Reference Laboratory (SHRL) Coagulation department will go live with a new lot of Prothrombin Time (Protime/PT) reagents. The reference range for the PT will be adjusted to reflect this reagent lot change and align with our Regional Laboratories. The new reference range will be 9.5 – 12.0 seconds. There will be no change to the INR ranges.

Test Current Reference Range New Reference Range
Prothrombin Time (PT) 9.7 – 12.6 seconds 9.5 – 12.0 seconds

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Hemostasis/Coagulation

aPTT Range Update for Heparin Nomograms

On Tuesday October 26, 2021, a new lot of aPTT reagent will go live for the Spectrum Health Laboratory Information System starting at 10:00 AM.

• The aPTT therapeutic range for ADULT patients on continuous heparin infusions will be updated to reflect the new reagents.  The therapeutic range, for most indications, will be changed from 37 to 52 seconds to a new range of 42 to 57 seconds. UFH anti-Xa therapeutic ranges will remain unchanged (0.3 to 0.7 units/mL).  All ADULT nomograms will be adjusted to reflect the new therapeutic ranges.

• For PEDIATRIC  patients, aPTT nomograms will no longer be used in this population. Only the unfractionated heparin (UFH) anti-Xa nomograms will remain for PEDIATRIC patients, again with no changes made to their current UFH anti-Xa nomograms.

The aPTT reference range remains unchanged. Continue Reading