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Hemostasis/Coagulation

General Information, Hemostasis/Coagulation

Reference Range Updates Coagulation Laboratory

Effective December 2, 2024 at 08:00 AM, Corewell Health West Laboratory Coagulation Department will be updating the reference range for several assays. The following will be impacted by these changes:

APTT testing for the BCS XP analyzers will be updating to 22.0 – 27.0 seconds.

This will include the following tests:

Effective December 2, 2024 at 08:00 AM, the Corewell Health West and South Coagulation Departments will be updating the reference range of the Fibrinogen Level (LAB 314) to 190-450 mg/ dL.

Questions may be directed to the Coagulation Laboratory using the Contact Us link above.

November 27, 2024 by
General Information, Hemostasis/Coagulation

New Test: UFH Anti-IIa

Effective August 23, 2023, Corewell Health Coagulation Laboratory will go live with UFH Anti-IIa testing.

The Anti-IIa 2 stage heparin assay is a chromogenic assay for measuring the activity of unfractionated heparin.  This method only tests unfractionated heparin.

This heparin assay is a two stage Anti IIa ( 2 Stages Heparin Assay) based on the inhibition of a constant amount of Thrombin (IIa) by the tested heparin in the presence of exogenous antithrombin. Continue Reading

August 22, 2023 by
General Information, Hemostasis/Coagulation

Test Update: Prothrombin Time (Protime/PT)

Effective December 6, 2021, Spectrum Health Reference Laboratory (SHRL) Coagulation department will go live with a new lot of Prothrombin Time (Protime/PT) reagents. The reference range for the PT will be adjusted to reflect this reagent lot change and align with our Regional Laboratories. The new reference range will be 9.5 – 12.0 seconds. There will be no change to the INR ranges.

Test Current Reference Range New Reference Range
Prothrombin Time (PT) 9.7 – 12.6 seconds 9.5 – 12.0 seconds

Continue Reading

December 3, 2021 by
Hemostasis/Coagulation

aPTT Range Update for Heparin Nomograms

On Tuesday October 26, 2021, a new lot of aPTT reagent will go live for the Spectrum Health Laboratory Information System starting at 10:00 AM.

• The aPTT therapeutic range for ADULT patients on continuous heparin infusions will be updated to reflect the new reagents.  The therapeutic range, for most indications, will be changed from 37 to 52 seconds to a new range of 42 to 57 seconds. UFH anti-Xa therapeutic ranges will remain unchanged (0.3 to 0.7 units/mL).  All ADULT nomograms will be adjusted to reflect the new therapeutic ranges.

• For PEDIATRIC  patients, aPTT nomograms will no longer be used in this population. Only the unfractionated heparin (UFH) anti-Xa nomograms will remain for PEDIATRIC patients, again with no changes made to their current UFH anti-Xa nomograms.

The aPTT reference range remains unchanged. Continue Reading

October 21, 2021 by
Hemostasis/Coagulation

Update: PT/INR Resulting Change

The Spectrum Health Laboratory Coagulation Department announces the following changes occurring on 6.29.21 because of new instrumentation:

• New coagulation instrumentation will go-live on 6.29.21.

• This new instrumentation will align the Spectrum Health Regional Laboratory (in GR) with current Regional/Blodgett reportable upper limit for Protime/INR results.

• The current Protime (PT) upper limit of 120 seconds will change to 90 seconds. Any result that is greater than 90 seconds, will be reported as >90 seconds.

• The current INR upper limit of 12.0 will change to 8.0. Any result that is greater than 8.0 will be reported as >8.0.

Any questions can be directed to the Spectrum Health Regional Laboratory Coagulation Department using the Contact Us link above.

TEST INFORMATION 

PT/INR (Protime with INR): Epic Code #LAB320 | Interface code #10059 | CPT #85610

June 29, 2021 by