ffective June 2, 2026, Paraneoplastic Autoantibody Evaluation will no longer be offered by Mayo. The recommended alternate test will be the Encephalitis Antibody Evaluation performed at Quest.
Due to the short notice from Mayo, the new Quest test will not be orderable so will need to be ordered as a Reference Lab Sendout for Miscellaneous Test.
Body Fluid Culture – Specimen Collection Update
Effective June 1, 2026, Corewell Health Microbiology Laboratory in Southeast Michigan is updating specimen collection criteria for body fluid specimens. Microbiology will no longer accept red top vacutainer tubes as a collection device for body fluids (i.e. synovial fluid, pleural fluid, peritoneal fluid, etc). Collection criteria information has been updated in Corewell’s Lab Test Directory to reflect this change. Test order for body fluid cultures is LAB2111016 (aerobic culture) and commonly accompanied by LAB233 (anaerobic culture).
Changes to Outpatient Occult Blood (FIT) Stool Testing (Corewell Health Southwest Region)
Effective Tuesday, May 26, 2026, outpatient occult blood testing (stool) will no longer be performed at Corewell Health Lakeland St. Joseph Laboratory and will instead be routed or mailed to Corewell Health Reference Laboratory in Grand Rapids, MI (35 Michigan St.) for processing.
In addition, the collection kits will be updated from OC-Light™ S FIT collection kits to OC-Auto™ collection kits.
Client Letter Update: Diagnostic Lab of Michigan
Click here to read the full letter
Effective Wednesday, April 29, 2026, Schistocyte Review (LAB1231565) will be available to order across all Corewell Health Laboratories Hematology Departments.
This new orderable supports alignment across Corewell Health regions by standardizing schistocyte assessment practices, ensuring high‑quality testing, and delivering a consistent patient care experience system‑wide.
This monthly bulletin includes updates about insurance payor nuances, diagnosis coding reminders, and other helpful tips and information regarding all things laboratory billing.
If you have any questions, please reach out to your laboratory account manager.
When ordering a Pre‑surgical Type & Screen, all required order questions must be completed accurately. These answers drive specimen routing, collection timing, and blood bank workflow in Epic.
Effective 4/15/2026, in accordance with the 2024 American College of Medical Genetics and Genomic Technical Laboratory Standards, the Acute Myeloid Leukemia (AML) Probe Panel by FISH will now include:
• -5/5q Deletion
• -7/7q Deletion
• RUNX1::RUNX1T1 t(8;21) Fusion
• NUP98 (11p15.4) Rearrangement
• KMT2A (MLL) (11q23) Rearrangement
• CBFB::MYH11 inv(16) and t(16;16) Fusion
• TP53 (17p13.1) Deletion
The panel will no longer include BCR::ABL t(9;22) and PML::RARA t(15;17). These tests may still be ordered independently.
Additional Resource Link: ACMG Technical Standard Section E6.1-6.6 of the American College of Medical Genetics and Genomics (ACMG) Technical Laboratory Standards: Cytogenomic studies of acquired chromosomal abnormalities in neoplastic blood, bone marrow, and lymph nodes (https://www.gimjournal.org/article/S1098-3600(23)01070-5/fulltext)
Epic Code: LAB2111348
