General Information

Paraneoplastic Autoantibody Evaluation

ffective June 2, 2026, Paraneoplastic Autoantibody Evaluation will no longer be offered by Mayo.  The recommended alternate test will be the Encephalitis Antibody Evaluation performed at Quest.

Due to the short notice from Mayo, the new Quest test will not be orderable so will need to be ordered as a Reference Lab Sendout for Miscellaneous Test.

The new orderable test will be available July 8, 2026. Continue Reading

Dearborn, Farmington Hills, Grosse Pointe, Royal Oak, Southeast Michigan, Taylor, Trenton, Troy, Wayne

Body Fluid Culture – Specimen Collection Update

Effective June 1, 2026, Corewell Health Microbiology Laboratory in Southeast Michigan is updating specimen collection criteria for body fluid specimens. Microbiology will no longer accept red top vacutainer tubes as a collection device for body fluids (i.e. synovial fluid, pleural fluid, peritoneal fluid, etc). Collection criteria information has been updated in Corewell’s Lab Test Directory to reflect this change. Test order for body fluid cultures is LAB2111016 (aerobic culture) and commonly accompanied by LAB233 (anaerobic culture). Continue Reading

Niles, Southwest Michigan, St. Joseph, Watervliet

Changes to Outpatient Occult Blood (FIT) Stool Testing (Corewell Health Southwest Region)

Effective Tuesday, May 26, 2026, outpatient occult blood testing (stool) will no longer be performed at Corewell Health Lakeland St. Joseph Laboratory and will instead be routed or mailed to Corewell Health Reference Laboratory in Grand Rapids, MI (35 Michigan St.) for processing.

In addition, the collection kits will be updated from OC-Light™ S FIT collection kits to OC-Auto™ collection kits. Continue Reading

Corewell Health System, Hematology

Schistocyte Review Test Now Available to Order

Effective Wednesday, April 29, 2026, Schistocyte Review (LAB1231565) will be available to order across all Corewell Health Laboratories Hematology Departments.

This new orderable supports alignment across Corewell Health regions by standardizing schistocyte assessment practices, ensuring high‑quality testing, and delivering a consistent patient care experience system‑wide.

Continue Reading

Blood Bank, Compliance & Safety, Corewell Health System

Reminder Pre‑Surgical Type & Screen Orders

When ordering a Pre‑surgical Type & Screen, all required order questions must be completed accurately. These answers drive specimen routing, collection timing, and blood bank workflow in Epic.

Epic uses your responses to ensure testing is performed by the correct blood bank at the correct time. Incomplete or incorrect information can result in misrouted specimens, delays, rework, or redraws.

Continue Reading

General Information

Updated: Acute Myeloid Leukemia (AML) Probe Panel by FISH

Effective 4/15/2026, in accordance with the 2024 American College of Medical Genetics and Genomic Technical Laboratory Standards, the Acute Myeloid Leukemia (AML) Probe Panel by FISH will now include:

• -5/5q Deletion
• -7/7q Deletion
• RUNX1::RUNX1T1 t(8;21) Fusion
• NUP98 (11p15.4) Rearrangement
• KMT2A (MLL) (11q23) Rearrangement
• CBFB::MYH11 inv(16) and t(16;16) Fusion
• TP53 (17p13.1) Deletion

The panel will no longer include BCR::ABL t(9;22) and PML::RARA t(15;17). These tests may still be ordered independently.

Additional Resource Link: ACMG Technical Standard Section E6.1-6.6 of the American College of Medical Genetics and Genomics (ACMG) Technical Laboratory Standards: Cytogenomic studies of acquired chromosomal abnormalities in neoplastic blood, bone marrow, and lymph nodes (https://www.gimjournal.org/article/S1098-3600(23)01070-5/fulltext)

Epic Code: LAB2111348