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Toxicology

Discontinuation Pyruvic Acid

Effective Wednesday, November 29, 2023, the in-house test, Pyruvic Acid, will be made inactive. Recommended alternative testing is Pyruvic Acid, Blood [LAB1231461] which is referred to Mayo Clinic Laboratories. Please review the lab catalog for information on new specimen requirements and updated reference range information. Due to the update in reference ranges, this may disrupt trending data.

The test Lactate/Pyruvate Ratio will also be inactivated with no alternative testing. If you require assistance with obtaining the ratio, please Contact Us. Continue Reading

General Information, Hematology

CBC Unit Updates

On Monday, November 20, 2023, Corewell Health Laboratories West will adjust several hematology result components units of measure. The numerical results will be unchanged, the metric units will be adjusted to achieve standardization across the system and will align our labs with the International Society of Laboratory Hematology’s recommendations for standardization of hematology reporting units in blood counts.

The following parameter will be adjusted because of this change: Continue Reading

Microbiology

Test Update: Influenza Rapid and RSV Rapid Tests Discontinued

Effective October 3, 2023, Corewell Health Laboratories will discontinue the Influenza Rapid and Respiratory Syncytial Virus (RSV) Rapid tests. These antigen tests are less sensitive than the nucleic acid amplification tests (NAAT; such as PCR) that are now the standard of care for diagnosing these respiratory viruses. Specimen collection remains unchanged with PCR testing available for nasopharyngeal and nasal swabs collected in a universal transport media (UTM) tube.

Discontinued:

• Influenza (Flu) A/B Rapid – Epic Code: LAB9240
• Influenza (Flu) A/B Rapid, Influenza A/B PCR if Negative – Epic Code: LAB2111530
• Respiratory Syncytial Virus (RSV) Rapid – Epic Code: LAB495

Replace with:

• Influenza (Flu) A/B PCR – Epic Code: LAB3255
• COVID-19, Influenza A/B, RSV PCR – Epic Code: LAB1230746

General Information, Hemostasis/Coagulation

New Test: UFH Anti-IIa

Effective August 23, 2023, Corewell Health Coagulation Laboratory will go live with UFH Anti-IIa testing.

The Anti-IIa 2 stage heparin assay is a chromogenic assay for measuring the activity of unfractionated heparin.  This method only tests unfractionated heparin.

This heparin assay is a two stage Anti IIa ( 2 Stages Heparin Assay) based on the inhibition of a constant amount of Thrombin (IIa) by the tested heparin in the presence of exogenous antithrombin. Continue Reading

Microbiology

Sinus Culture Order Considerations

The management of sinusitis is often aided by bacterial and fungal cultures from which Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, Staphylococcus aureus, and occasionally aerobic Gram-negative bacilli are the most commonly recovered pathogenic organisms. The Corewell Health West Microbiology Lab has several orders available for culturing sinus specimens collected as fluid aspirates, tissue, or swabs. Though more challenging to collect, aspirates are preferred over swab cultures that often grow mixed normal upper respiratory flora for which it is difficult to interpret the clinical significance.

Available Sinus Culture Orders Default Specimen Type Comments
Body Fluid Culture [LAB2111016]

Respiratory Culture [LAB3095]

Tissue Culture [LAB2111173]

Aspirated fluid

Swabbed collection

Tissue

For aerobic bacteria
Fungal Culture [LAB240] Aspirated fluid or tissue, preferred

Swabbed collection

For fungal organisms
Anaerobic Culture [LAB233] Aspirated fluid or tissue* For anaerobic bacteria

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Education & Training, General Information, Immunochemistry, Test Utilization

Webinar: Optimizing Care of the Respiratory Patient – The Role of Specific IgE Testing

It’s the season of sunshine and blooms which also means it can be a season of sneezing, itching, and a lot of trouble getting a good breath in for some.

⇒Are you prepared to meet the needs of your patients that may be suffering from some of these symptoms?
⇒Are you well versed in the difference between a sensitivity and a clinical allergy and how you can differentiate between the two?
⇒Do you know the resources we have at Corewell Health to assist in these determinations? Continue Reading