Chemistry

Vitamin D Test Ordering Update

Effective June 4, 2025, Corewell Health Laboratory will update Vitamin D testing. The following Vitamin D tests will be available in conjunction with ordering recommendations to assist providers on the appropriate selection of Vitamin D testing:

  • Ordering Recommendation: preferred test to diagnose Vitamin D insufficiency and monitor response to therapy.
  • Testing is recommended only for patients at risk for Vitamin D insufficiency.
  • Ordering Recommendation: For evaluating calcium metabolism in individuals with hypercalcemia or renal failure in addition to Vitamin D, 25-Hydroxy testing.
  • Test is not appropriate for diagnosing vitamin D deficiency or insufficiency.

25-Hydroxyvitamin D2 and D3 by Tandem Mass Spectrometry, Serum and Plasma

  • Ordering Recommendation: May be useful for individuals with vitamin D insufficiency/deficiency who are not responding to supplementation.
  • Not the test of choice for initial evaluation of vitamin D insufficiency; Vitamin D, 25-Hydroxy is preferred.
For additional requests, questions, suggestions, or interface codes please use the contact us link above.
TEST INFORMATION
  • Vitamin D, 25-Hydroxy [LAB1231583]
  • Vitamin D, 1, 25-Dihydroxy [LAB1231384]
  • 25-Hydroxyvitamin D2 and D3 [LAB1230925]
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